Modulation of Arachidonic Acid Metabolism by Chemopreventive Agents in Smokers
Study Status
Closed to Enrollment
Study Description
We are seeking healthy male and female current smokers to participate in a research study. Participation involves:
- Giving a brief interview
- Collection of blood and urine
- Taking one or two medications (as pills) for seven days in a row, either an asthma medication called zileuton, or zileuton plus an arthritis medication called delecoxib
- Eligible volunteers will be financially compensated for completing the study requirements
The purpose of this study is to learn more about the effects of taking the drugs zileuton or zileuton and celexocib on certain chemicals in the the body that are thought to be associated with smoking-related lung disease risk. Currently there are not enough ways to decrease smoking-related disease. We hope this study will provide information that can be used in the future to develop approaches using these medications or related medications to reduce the risk of smoking-related diseases.
Please visit our website http://nyp.org/zileutoncelecoxib.html for more information about participating in this study.
Sponsor
National Cancer Institute/Division of Cancer Prevention (NCI/DCP)
Key Eligibility
- Healthy male and female current smokers
Principal Investigator
Contact
- Allison Knutson, CCRP
- 212-746-9945
- [email protected]
Healthy Volunteers
As a healthy volunteer in a clinical trial you may make a significant contribution to the discovery of medical knowledge and new treatments that could impact people around the world.
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Contact Us
For general inquiries, or if you need assistance finding a study, please contact:
Robert Hagerty
Subject Recruitment Manager
Tel: (646) 962-9340
[email protected]