Solid Tumor
Show Only Open Trials
1.
GO27983: A Phase Ib/II Study of GDC-0068 or GDC-0980 with Abiraterone Acetate versus Abiraterone Acetate in Patients with Castration-Resistant Prostate Cancer Previously Treated with Docetaxel-Based Chemotherapy
- Study Status: Open to Enrollment
- Sponsor: Genentech
- Disease Status and/or Stage: Metastatic or Advanced Prostate Cancer
- Protocol ID: GO27983
2.
A Double-blind, Placebo-controlled Study to Evaluate New or Worsening Lens Opacifications in Subjects with Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss due to Androgen-Deprivation Therapy
- Study Status: Open to Enrollment
- Sponsor: Amgen
- Disease Status and/or Stage: Prostate Cancer Receiving Androgen Deprivation Therapy
3.
A Phase 2, Open-label, Multicenter Study of PSMA ADC in Subjects with Metastatic Castration-resistant Prostate Cancer (mCRPC)
- Study Status: Open to Enrollment
- Sponsor: PSMA Development Company
- Disease Status and/or Stage: Metastatic Castration-Resistant Prostate Cancer
- Protocol ID: PSMA ADC 2301
4.
S1216: Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer
- Study Status: Open to Enrollment
- Sponsor: SWOG
- Disease Status and/or Stage: Metastatic Prostate Cancer
- Protocol ID: S1216
5.
CALGB 30801: A Randomized Phase III Double Blind Trial Evaluating Selective COX-2 Inhibition in COX-2 Expressing Advanced Non-Small Cell Lung Cancer
- Study Status: Closed to Enrollment
- Sponsor: CALGB
- Disease Status and/or Stage: Non Small Cell Lung Cancer (NSCLC)
- Protocol ID: CALGB 30801
6.
A Phase 1a/b Non-Randomized, Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Sterile Compound 31510 (Ubidecarenone, USP) Nanosuspension for Injection Administered Intravenously to Patients with Solid Tumors
- Study Status: Open to Enrollment
- Sponsor: Berg Pharma
- Disease Status and/or Stage: Advanced Solid Tumors
7.
Clinical Performance, Efficacy and Safety of the DigniCap System, a Scalp Hypothermia System, in Preventing Chemotherapy Induced Alopecia in Patients with Early Stage Breast Cancer
- Study Status: Open to Enrollment
- Sponsor: Dignitana AB
- Disease Status and/or Stage: Stage I or II Breast Cancer
- Protocol ID: DIG-001
8.
Analysis of Hematopoietic Progenitor Cells and Endothelial Progenitor Cells to Predict Early Relapse of Treated Non-Small-Cell Lung Cancer (NSCLC): A Pilot Study
- Study Status: Open to Enrollment
- Sponsor: Weill Cornell Medical College
- Disease Status and/or Stage: Non-Small Cell Lung Cancer
9.
10.
A Phase III Study of Onartuzumab (MetMAb) in Combination With mFOLFOX6 in Patients With Metastatic HER2-Negative And Met-Positive Gastroesophageal Cancer (MetGastric)
- Study Status: Open to Enrollment
- Sponsor: Genentech
- Disease Status and/or Stage: Metastatic Gastric Cancer
- Protocol ID: YO28322
11.
LUX-Lung 8: A randomized, open-label Phase III trial of afatinib versus erlotinib in patients with advanced squamous cell carcinoma of the lung as second-line therapy following first-line platinum-based chemotherapy
- Study Status: Closed to Enrollment
- Sponsor: Boehringer Ingelheim Pharmaceuticals
- Disease Status and/or Stage: Previously Treated Advanced Squamous Cell Lung Cancer
12.
A Randomized, Open-Label, Phase 3 Study of BMS-936558 vs Everolimus in Subjects with Advanced or Metastatic Clear-Cell Renal Cell Carcinoma Who Have Received Prior Anti-Angiogenic Therapy
- Study Status: Open to Enrollment
- Sponsor: Bristol-Myers Squibb
- Disease Status and/or Stage: Advanced or Metastatic Kidney Cancer
- Protocol ID: BMS CA209-025-041
13.
A Phase 3, Randomized, Double-blind, Controlled Study of Cabozantinib (XL184) vs. Prednisone in Metastatic Castration-resistant Prostate Cancer Patients who have Received Prior Docetaxel and Prior Abiraterone or MDV3100
- Study Status: Open to Enrollment
- Sponsor: Exelixis
- Disease Status and/or Stage: Metastatic Castration-Resistant Prostate Cancer
- Protocol ID: XL184-307
14.
A Phase II Trial of the Aurora Kinase A Inhibitor MLN8237 in Patients with Metastatic Castrate Resistant and Neuroendocrine Prostate Cancer
- Study Status: Open to Enrollment
- Sponsor: Weill Cornell Medical College
15.
An Open Label Multicenter Phase 2 Window of Opportunity Study Evaluating Ganetespib (STA-9090) Monotherapy in Women with Previously Untreated Metastatic HER2 Positive or Triple Negative Breast Cancer
- Study Status: Open to Enrollment
- Sponsor: Synta
- Disease Status and/or Stage: Previously Untreated Metastatic HER2-Positive or Triple Negative Breast Cancer
16.
A Double-blind, Randomized Phase II Trial of Active Immunotherapy with Globo H-KLH (OPT-822) in Subjects with Metastatic Breast Cancer
- Study Status: Open to Enrollment
- Sponsor: Optimer Biotechnology
- Disease Status and/or Stage: Metastatic Breast Cancer
17.
A Phase I/II Trial of Temsirolimus Plus Neratinib for Subjects with Metastatic HER2-Amplified or Triple Negative Breast Cancer
- Study Status: Open to Enrollment
- Sponsor: Puma
- Disease Status and/or Stage: HER2-Positive Metastatic Breast Cancer
18.
Phase I Study of IMMU-132 (hRS7-SN38 Antibody Drug Conjugate) in Patients with Epithelial Cancer
- Study Status: Open to Enrollment
- Sponsor: Immunomedics
- Disease Status and/or Stage: Metastatic Epithelial Cancer
19.
A Study of Trastuzumab Emtansine Versus Taxane in Patients With Advanced Gastric Cancer
- Study Status: Open to Enrollment
- Sponsor: Hoffmann-La Roche/Genentech
- Disease Status and/or Stage: Advanced or Metastatic HER2-Positive Gastric or GEJ Cancer
- Protocol ID: BO27952
20.
The BEACON Study (Breast Cancer Outcomes With NKTR-102)
- Study Status: Open to Enrollment
- Sponsor: Nektar Therapeutics
- Disease Status and/or Stage: Locally Recurrent or Metastatic Breast Cancer Previously Treated with Cytotoxic Chemotherapy
21.
Fludeoxyglucose F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer
- Study Status: Open to Enrollment
- Sponsor: NCI
- Disease Status and/or Stage: Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer
22.
A phase III trial of adjuvant chemotherapy following chemoradiation as primary treatment for locally advanced cervical cancer compared to chemoradiation alone: THE OUTBACK TRIAL
- Study Status: Open to Enrollment
- Sponsor: Gynecologic Oncology Group; National Cancer Institute
- Disease Status and/or Stage: Locally Advanced Cervical Cancer
23.
Phase II Trial of Combination Pemetrexed (Alimta) and Carboplatin (Paraplatin) in Platinum Sensitive Recurrent Ovarian, Primary Peritoneal, and Fallopian Tube Carcinoma
- Study Status: Open to Enrollment
- Sponsor: Montefiore Medical Center
- Disease Status and/or Stage: Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer
24.
A Phase Ib Study of Fractionated 90Y-hPAM4 with or without Gemcitabine in Patients with Metastatic Pancreatic Cancer who Received at Least Two Prior Treatments
- Study Status: Closed to Enrollment
- Sponsor: Immunomedics
- Disease Status and/or Stage: Stage IV Metastatic Pancreatic Cancer
- Protocol ID: IM-T-hPAM4-03
25.
An Open-Labeled, Multicenter Phase II Study of Cabazitaxel in Refractory Metastatic Gastric or Gastroesophageal Adenocarcinoma
- Study Status: Open to Enrollment
- Sponsor: Weill Cornell Medical College
- Disease Status and/or Stage: Metastatic Gastric or Gastroesophageal (GEJ) Cancer
26.
N093B: Phase I/II Study of Panobinostat (LBH589) and Letrozole in Patients with Triple Negative Metastatic Breast Cancer
- Study Status: Open to Enrollment
- Sponsor: Cancer Trials Support Unit (CTSU)
- Disease Status and/or Stage: Triple Negative Metastatic Breast Cancer
- Protocol ID: N093B
27.
PRESENT: Prevention of Recurrence in Early-Stage, Node-Positive Breast Cancer with Low to Intermediate HER2 Expression with NeuVaxâ„¢ Treatment
- Study Status: Open to Enrollment
- Sponsor: Galena Biopharma
- Disease Status and/or Stage: HER2 1+/2+, Node Positive Breast Cancer
28.
An Open-label Phase 2 Study of ACE-041 in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
- Study Status: Closed to Enrollment
- Sponsor: Acceleron
- Disease Status and/or Stage: Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck
29.
A Study of Trastuzumab in Combination With Cisplatin/Capecitabine Chemotherapy in Patients With HER2-Positive Metastatic Gastric or Gastro-Esophageal Junction Cancer
- Study Status: Open to Enrollment
- Sponsor: Genentech/Roche
- Disease Status and/or Stage: Metastatic Gastric Cancer
30.
CALGB 80702: A Phase III Trial of 6 versus 12 Treatments of Adjuvant Folfox Plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer
- Study Status: Open to Enrollment
- Sponsor: CALGB
- Disease Status and/or Stage: Resected Stage III Colon Cancer
- Protocol ID: CALGB 80702
31.
A randomized, double-blind, placebo-controlled phase III study to evaluate the efficacy and safety of pazopanib as adjuvant therapy for subjects with localized or locally advanced RCC following nephrectomy
- Study Status: Open to Enrollment
- Sponsor: GlaxoSmithKline
- Disease Status and/or Stage: Kidney Cancer, Surgically Removed
32.
CALGB 70807: The Men's Eating and Living (MEAL) Study: A Randomized Trial of Diet to Alter Disease Progression in Prostate Cancer Patients on Active Surveillance
- Study Status: Open to Enrollment
- Sponsor: CALGB
33.
E1505: A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients With Completely Resected Stage IB (> 4 cm) -IIIA Non-Small Cell Lung Cancer (NSCLC)
- Study Status: Open to Enrollment
- Sponsor: Eastern Cooperative Oncology Group
34.
REO 022: A Multicenter Phase 1 Study of Intravenous Administration of REOLYSIN® (Reovirus Type 3 Dearing) in Combination with Irinotecan/Fluorouracil/Leucovorin (FOLFIRI) in Patients with Oxaliplatin Refractory/Intolerant KRAS Mutant Colorectal Cancer
- Study Status: Closed to Enrollment
- Sponsor: Oncolytics Biotech, Inc.
- Disease Status and/or Stage: Colon Cancer
35.
REO 017: A Phase 2 Study of Reolysin® in Combination with Gemcitabine for Patients with Advanced Pancreatic Adenocarcinoma
- Study Status: Closed to Enrollment
- Disease Status and/or Stage: Advanced or Metastatic Pancreatic Cancer
36.
A Phase II Study of Tetrathiomolybdate (TM) in patients with breast cancer at moderate to high risk of recurrence
- Study Status: Open to Enrollment
- Sponsor: Weill Cornell Medical College
- Disease Status and/or Stage: High-Risk Stage II Breast Cancer; Stage III Breast Cancer; Stage IV Breast Cancer in Remission
37.
Prospective Data Collection Among Women Using Cold Caps During TC Chemotherapy
- Study Status: Open to Enrollment
- Disease Status and/or Stage: Early-Stage Breast Cancer
38.
A Randomized, Double-Blind, Phase 3 Study of Docetaxel and Ramucirumab versus Docetaxel and Placebo in the Treatment of Stage IV Non-Small Cell Lung Cancer Following Disease Progression after One Prior Platinum-Based Therapy
- Study Status: Open to Enrollment
- Sponsor: Lilly
- Disease Status and/or Stage: Stage IV Non-Small Cell Lung Cancer
39.
A Phase 1b Safety Study of Abiraterone Acetate (JNJ 212082) and Docetaxel in Subjects with Metastatic Castration-Resistant Prostate Cancer (mCRPC) (COU-AA-206)
- Study Status: Open to Enrollment
- Sponsor: Cougar Biotechnology
- Disease Status and/or Stage: Metastatic Castration-Resistant Prostate Cancer
40.
A Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy Versus Immediate Radical Prostatectomy in Patients with High-Risk, Clinically Localized Prostate Cancer
- Study Status: Open to Enrollment
- Sponsor: Cancer and Leukemia Group B, National Cancer Institute
- Disease Status and/or Stage: High Risk, Clinically Localized Prostate Cancer
- Protocol ID: CALGB 90203
41.
A Randomized Phase 2 Trial of 177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and ketoconazole in Patients with High-Risk Castrate Biochemically Relapsed Prostate Cancer After Local Therapy
- Study Status: Open to Enrollment
- Sponsor: Weill Cornell Medical College
- Disease Status and/or Stage: Relapsed Prostate Cancer
42.
A Phase I Trial of Docetaxel/Prednisone plus Fractionated 177Lu-J591 Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody in Patients with Metastatic, Castrate-Resistant Prostate Cancer
- Study Status: Open to Enrollment
- Sponsor: Weill Cornell Medical College
- Disease Status and/or Stage: Metastatic Prostate Cancer
43.
A Phase III trial of short term androgen deprivation with pelvic lymph node or prostate bed only radiotherapy (SPPORT) in prostate cancer patients with a rising PSA after radical prostatectomy
- Study Status: Open to Enrollment
- Sponsor: Radiation Therapy Oncology Group, National Cancer Institute
- Disease Status and/or Stage: Prostate Cancer After Radical Prostatectomy
44.
A Phase 1B, Open-Label, Dose Escalation Study Evaluating the Safety of BSI-201 in Combination with Chemotherapeutic Regimens in Subjects with Advanced Solid Tumors
- Study Status: Closed to Enrollment
- Sponsor: BiPar Sciences
- Disease Status and/or Stage: Metastatic Pancreatic Cancer
45.
A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase 2 Study of the Efficacy and Safety of Apricoxib in Combination with either Docetaxel or Pemetrexed in Non-Small Cell Lung Cancer Patients
- Study Status: Open to Enrollment
- Sponsor: Tragara Pharmaceuticals
- Disease Status and/or Stage: Stage IIIB/IV or Recurrent, Unresectable Non-Small Cell Lung Cancer
46.
Chemotherapy and Radiation in Treating Patients With Stage 3 Non-Small Cell Lung Cancer (PROCLAIM)
- Study Status: Open to Enrollment
- Sponsor: Eli Lily & Co.
- Disease Status and/or Stage: Unresectable, Locally Advance, Stage III Non-Small Cell Lung Cancer
47.
A Phase I/II Study of Vorinostat in Combination with Isotretinoin in the Treatment of Patients with Advanced Renal Cell Carcinoma
- Study Status: Closed to Enrollment
- Sponsor: Weill Cornell Medical College, National Cancer Institute
- Disease Status and/or Stage: Metastatic or Advanced Kidney Cancer
48.
A Phase I/II Trial of BAY 43-9006 plus Gemcitabine and Capecitabine in the Treatment of Patients with Advanced Renal Cell Carcinoma
- Study Status: Closed to Enrollment
- Sponsor: Weill Cornell Medical College, National Cancer Institute
- Disease Status and/or Stage: Advanced, Unresectable and/or Metastatic Kidney Cancer
49.
ECOG 2805: A Randomized, Double-Blind Phase III Trial of Adjuvant Sunitinib versus Sorafenib versus Placebo in Patients with Resected Renal Cell Carcinoma (RCC)
- Study Status: Closed to Enrollment
- Sponsor: Eastern Cooperative Oncology Group
- Disease Status and/or Stage: Renal Cell Cancer
50.
A Phase II Trial of Temsirolimus and Bevacizumab in Patients With Endometrial, Ovarian, Hepatocellular Carcinoma, Carcinoid and Islet Cell Cancer
- Study Status: Closed to Enrollment
- Sponsor: Mayo Clinic, National Cancer Institute
- Disease Status and/or Stage: Locally Advanced, Recurrant or Metastatic disease
51.
A Randomized Double-Blinded Phase III Study Comparing Gemcitabine, Cisplatin, and Bevacizumab to Gemcitabine, Cisplatin, and Placebo in Patients With Advanced Transitional Cell Carcinoma
- Study Status: Open to Enrollment
- Sponsor: Cancer and Leukemia Group B (CALGB); National Cancer Institute (NCI)
- Disease Status and/or Stage: Advanced Transitional Cell Carcinoma
52.
A Phase I Study of 177Lu Radiolabeled Monoclonal Antibody HuJ591-GS (177Lu-591) in Patients with Nonprostate Metastatic Solid Tumors: A Pilot Study
- Study Status: Open to Enrollment
- Sponsor: Weill Cornell Medical College
- Disease Status and/or Stage: Metastatic Solid Tumor
53.
A Phase II, Multicenter, Randomized, Open-Label Study Comparing Eribulin Mesylate and Ixabepilone in Causing or Exacerbating Neuropathy in Patients with Advanced Breast Cancer
- Study Status: Open to Enrollment
- Sponsor: Eisai
- Disease Status and/or Stage: Advanced Breast Cancer and Neuropathy
54.
Phase II study of ixabepilone in patients with metastatic breast cancer and a prospective evaluation of its effects on the ultrastructure of neurons
- Study Status: Open to Enrollment
- Sponsor: Weill Cornell Medical College; Bristol-Myers Squibb
- Disease Status and/or Stage: Metastatic Breast Cancer
55.
ACOSOG Z1072: A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma
- Study Status: Open to Enrollment
- Sponsor: American College of Surgeons/National Cancer Institute
- Disease Status and/or Stage: Invasive Breast Cancer
56.
A Randomized Placebo-Controlled Trial of Glutamine to Reduce the Signs and Symptoms of Peripheral Neuropathy in Breast Cancer Patients with a Mild Peripheral Neuropathy Receiving Paclitaxel Chemotherapy
- Study Status: Open to Enrollment
- Disease Status and/or Stage: Breast Cancer, any stage
57.
A Phase II Study of Tetrathiomolydate (TM) in patients with breast cancer at moderate to high risk for recurrence
- Study Status: Open to Enrollment
- Disease Status and/or Stage: Breast Cancer at moderate to high risk of recurrence (based on the number of lymph nodes); Stage 4 breast cancer without any evidence of disease
