A Phase I/II Trial of BAY 43-9006 plus Gemcitabine and Capecitabine in the Treatment of Patients with Advanced Renal Cell Carcinoma
Study Status
Closed to Enrollment
Study Description
This phase I/II trial is studying the side effects and best dose of sorafenib, gemcitabine, and capecitabine and to see how well they work in treating patients with unresectable and/or metastatic kidney cancer.
Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy, such as gemcitabine and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving sorafenib together with gemcitabine and capecitabine may kill more tumor cells.
Disease Status and/or Stage
Advanced, Unresectable and/or Metastatic Kidney Cancer
Sponsor
Weill Cornell Medical College, National Cancer Institute
Key Eligibility
- Men and women age 18 and over
- Diagnosed with unresectable and/or metastatic renal cell carcinoma (kidney cancer)
- Must have received prior chemotherapy-based regimen
- No prior chemotherapy or prior treatment with BAY 43-9006 and/or inhibitors of the MAPK or VEGF pathways
- Additional eligibility criteria to be discussed when you contact the study team
Principal Investigator
Contact
- Gina Mileo
- 212-746-5430
- [email protected]
Healthy Volunteers
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Contact Us
For general inquiries, or if you need assistance finding a study, please contact:
Erica Bersin
Tel: (646) 962-8232
[email protected]