An Open-label, Multicenter, Single-arm, Phase 2 Study of PCI-32765 (Ibrutinib) in Subjects with Refractory Follicular Lymphoma

Study Status

Open to Enrollment

Study Description

This clinical trial is for men and women with refractory follicular lymphoma who:

  • Have received at least 2 prior lines of therapy, and
  • Did not respond to the last prior therapy

The purpose of the study is to evaluate the response to treatment with an experimental drug called ibrutinib, also called PCI-32765.

Ibrutinib is an oral drug that inhibits the enzyme Bruton’s Tyrosine Kinase (BTK), decreasing the ability of lymphoma cells to grow and survive.

All study participants will receive ibrutinib; there is no placebo. Participants will take 4 capsules by mouth once every day. Participants will continue taking ibrutinib as long as they are responding to treatment and not experiencing unacceptable side effects.

Follow the Weill Cornell Lymphoma Program Online:


Twitter: @lymphomaprogram

Disease Status and/or Stage

Refractory Follicular Lymphoma



Key Eligibility

  • Age 18 and older
  • Refractory follicular lymphoma
  • Previously treated with at least 2 prior lines of therapy
  • Did not respond to last prior therapy
  • Detailed eligibility reviewed when you contact the study team

Principal Investigator

Peter Martin, MD


  • Amelyn Rodriguez, RN
  • (212) 746-1362
  • [email protected]
  • Weill Cornell Lymphoma Center
  • (646) 962-2700

Protocol ID


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Contact Us

For general inquiries, or if you need assistance finding a study, please contact:

Robert Hagerty
Subject Recruitment Manager
Tel: (646) 962-9340
[email protected]

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