A Randomized Placebo-Controlled Trial of Glutamine to Reduce the Signs and Symptoms of Peripheral Neuropathy in Breast Cancer Patients with a Mild Peripheral Neuropathy Receiving Paclitaxel Chemotherapy

Study Status

Open to Enrollment

Study Description

The purpose of this study is measure the effect of glutamine on peripheral neuropathy (numbness, tingling, pain or weakness in the hands and feet). Patients with breast cancer receiving paclitaxel chemotherapy who have mild symptoms of peripheral neuropathy will receive glutamine or placebo (something that looks like the study drug but contains no medicine) to try and improve symptoms.

Patients will receive glutamine or placebo packets mixed in a beverage on the day of the paclitaxel infusion and will thereafter take 10 grams glutamine or placebo by mouth three times daily for 4 days.

Disease Status and/or Stage

Breast Cancer, any stage

Key Eligibility

  • Patients with breast cancer
  • Are recieving paclitaxel chemotherapy
  • Have at least mild peripheral neuropathy (numbness, tingling, pain or weakness in the hands and feet)

Principal Investigator

Linda Vahdat, MD


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Contact Us

For general inquiries, or if you need assistance finding a study, please contact:

Erica Bersin
Tel: (646) 962-8232
[email protected]

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